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BICC1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9H694 |
| Other Accession | Q99MQ1, Q5U4T7, Q9IA00 |
| Reactivity | Human |
| Predicted | Xenopus, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 104844 Da |
| Antigen Region | 80-107 aa |
| Gene ID | 80114 |
|---|---|
| Other Names | Protein bicaudal C homolog 1, Bic-C, BICC1 |
| Target/Specificity | This BICC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-107 amino acids from the N-terminal region of human BICC1. |
| Dilution | IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BICC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BICC1 |
|---|---|
| Function | Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development. |
| Cellular Location | Cytoplasm. |
Provided below are standard protocols that you may find useful for product applications.
Background
BICC1 is an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product.
References
Grupe,A., et.al., Am. J. Hum. Genet. 78 (1), 78-88 (2006)
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